A vessel-on-a-chip model for anti-thrombotic pre-clinical testing (ISTH 2026) - May 25, 2026 - Abstract #PB3266; Pres time: Jul 14, 2026; 01:45 PM - 02:45 PM; Location: Exhibition Hall- Poster Area; "Results To assess the model's utility as a preclinical drug-testing platform, we examined the effect of the P2Y 12 inhibitor, cangrelor...By allowing anti-thrombotic agents to be tested directly using a platform that mimics the human blood vessel wall, this model has strong potential to improve translational relevance while reducing reliance on animal studies. Acknowledgement: We appreciate the NC3Rs for funding this research (NC/Y000870/1) DOI*10.1016/j.rpth.2026.105885"
Preclinical • Cardiovascular • Thrombosis
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Yan Wu 1; Jacob Ranjbar 2; Ying Yang 2; Alan Harper 2; Alice Pollitt 1
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