Platelet Phenotyping Predicts Ischemic Heart Disease (ISTH 2026) - May 25, 2026 - Abstract #OC 44.2; Pres time: Jul 13, 2026; 02:45 PM - 03:00 PM; Location: S05-06; "Platelet responses—Sensitivity (EC50) and Capacity (Emax)—were measured for fibrinogen binding and P-selectin exposure in response to three platelet agonists (ADP, CRP, TRAP-6) across multiple concentrations, with/without inhibitors (Cangrelor, Iloprost, Ibrutinib and PAPA NONOate). This may serve as a novel screening tool and identify patients with aberrant inhibitor responses, with potential to inform anti-platelet therapy. DOI*10.1016/j.rpth.2026.103680"
Cardiovascular • Coronary Artery Disease • Heart Failure
|
|
Joanne Dunster 1; Maria Diaz Alonso 1; Valentina Shpakova 1; Tanya Sage 1; Sharon Mark 2; Neline Kriek 1; Leanne Dymott 2; Craig Hughes 1; Alexander Bye 1; Chris Jones 1; Mark Brunton 2; Charlie McKenna 2; Neil Ruparelia 2; Jon Gibbins 1
|