In vitro evaluation of bicarbonate-formulated Pertzye drug product versus pancrelipase for triglyceride hydrolysis in an olive oil emulsion mixture (NACFC 2026) - Sep 9, 2026 - Abstract #553; "Bicarbonate-formulated pancreatic enzyme product, Pertzye, demonstrated higher triglyceride hydrolysis compared to non-bicarbonate pancrelipase. The observed differences in hydrolysis kinetics and pH profiles highlight the role of bicarbonate in the formulation and its impact on lipase enzyme activity. This may support a more efficient nutrient absorption, which is critical for nutritional management in CF-related EPI."
Preclinical • Cystic Fibrosis • Genetic Disorders • Immunology • Respiratory Diseases
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S. Das; Z. Luszik; T. Sipos.
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