Pharmacodynamic effects of cangrelor in patients with or without STEMI undergoing percutaneous coronary intervention: insights from the POMPEII study. (PubMed, Eur Heart J Acute Cardiovasc Care) - Apr 15, 2026 - P | "Cangrelor-induced platelet inhibition was lower in patients with STEMI compared to those without STEMI, and was lower than that induced by ticagrelor among STEMI patients. The switch from cangrelor to an oral P2Y12 inhibitor exposed patients without STEMI to greater HRPR compared to those with STEMI."
Journal • PK/PD data • Acute Coronary Syndrome • Cardiovascular • Myocardial Infarction
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Alessandra Spinelli; Anna Franzone; Carmen Anna Maria Spaccarotella; Domenico Florimonte; Domenico Simone Castiello; Eugenio Stabile; Fiorenzo Simonetti; Giovanni Esposito; Giuseppe Gargiulo; Imma Forzano; Lina Manzi; Luca Sperandeo; Luigi Di Serafino; Marco Valgimigli; Mario Enrico Canonico; Marisa Avvedimento; Plinio Cirillo; Raffaele Piccolo; Roberta Paolillo; Viviana Narciso
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