Correlation of the Eosinophilic Esophagitis Histology Scoring System With Peak Esophageal Eosinophil Counts: Pooled Analysis From the EoE KIDS and LIBERTY EoE TREET Studies (CAP 2026) - Aug 26, 2026 - Abstract #Poster No. 11; Pres time: Oct 4, 2026; 11:30 AM - 01:00 PM; Location: Cristal Ballroom Exhibit Hall; P3 | "Falk Pharma, Ferring, GI Reviewers, GSK, Holoclara, Invea, Knightpoint, LucidDx, Nexstone Immunology/Uniquity, Nutricia, Parexel/Calyx, Phathom, Regeneron, Revolo, Robarts/Alimentiv, Roivant, Sanofi, Shire/Takeda, Target RWE, Third Harmonic Bio, and Upstream Bio; and received research support from Adare/Ellodi, Allakos, Arena/Pfizer, AstraZeneca, Celgene/Receptos/BMS, Celldex, Dr. In this pooled analysis of 2 phase-3 EoE studies, strong correlations between EoEHSS grade/stage total scores and PEC were identified at W16/24 and W52. The EoEHSS also captured important histopathologic changes unrelated to eosinophil inflammation, valuable for disease diagnosis and monitoring in children and adults with EoE receiving dupilumab. Supported Collins received consulting fees from Alimentiv, Arena/Pfizer, AstraZeneca, Calypso Biotech, EsoCap Biotech, GSK, Receptos/Celgene/Bristol Myers Squibb, Regeneron Pharmaceuticals Inc, Sanofi, and Shire (a Takeda company)."
Retrospective data • Eosinophilic Esophagitis • Gastrointestinal Disorder • Immunology • Inflammation
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Margaret H. Collins, MD1; Evan S. Dellon, MD2; Kevin O. Turner, DO3; Christopher Ma, MD, MPH4; Salvatore Oliva, MD, PhD5; Matteo Fassan, MD, PhD6; Changming Xia, PhD7; Sherif Zaghloul, MD, MSc8; Sabina deMarchi, PharmD.9
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