The ALOX5-Mitochondrial oxidative stress link in quercetin-mediated nasal epithelial barrier protection in allergic rhinitis. (PubMed, Biochem Biophys Res Commun) - Jul 24, 2026 - "These findings suggest that an ALOX5-associated mitochondrial oxidative stress pathway contributes to HDM-induced nasal epithelial barrier dysfunction. Quercetin may protect epithelial barrier integrity in AR, at least partly by suppressing ALOX5/LTB4 signaling and mitochondrial oxidative injury."
Journal • Allergic Rhinitis • Immunology • Inflammation • ALOX5 • CDH1 • TJP1
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Fusen Peng; Mengfei Luo; Xinyu Liu
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