Beneficial effects of voclosporin on reducing proteinuria in lupus nephritis and extrarenal effects in SLE: insights form a small cohort with limited follow-up (ERA 2025) - Apr 15, 2025 - Abstract #597; Pres time: Jun 5, 2025; 10:21 AM - 10:24 AM; Location: Mozart Die Zauberflöte; "Treatments, including corticosteroids, rituximab, and cyclophosphamide, were recorded...One patient presented gingival hyperplasia remembering some patients under cyclosporine which has been controlled with mouth hygiene without voclosporin withdrawal and other patient presented a rash in the hip region which voclosporin collaborated in its improvement... Our preliminary findings suggest that voclosporin is effective, safe and valuable and provides a prompt improvement in proteinuria and serologic profile with extrarenal benefits in some cases, especially valuable in refractory patients. Further large-scale studies are needed to determine the long-term efficacy and safety and identify subgroups of patients who may benefit the most from it. Even further, despite its posology, patients maintained good compliance with voclosporin."
Cardiovascular • Diabetes • Glomerulonephritis • Immunology • Infectious Disease • Inflammatory Arthritis • Lupus • Lupus Nephritis • Metabolic Disorders • Nephrology • Pulmonary Arterial Hypertension • Renal Disease
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Marc Patricio Liébana1; Josefina Cortés Hernández2; Maria José Soler Romeo1; María Alejandra Gabaldón3; Marina López Martínez1; Sheila Bermejo Garcia1; Jorge Zamora Carrillo1; Héctor Luis Bedoya Orozco1; Sara Núñez- Delgado1; Oriol Bestard Matamoros1; Irene Agraz Pamplona1
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