Calcineurin inhibitor effects on kidney electrolyte handling and blood pressure: tacrolimus versus voclosporin. (PubMed, Nephrol Dial Transplant) - May 23, 2024 - "In contrast to tacrolimus, voclosporin does not cause hypercalciuria and hypomagnesemia, but similarly causes hypertension. Our data reveal differences between the distal tubular effects of tacrolimus and voclosporin and provide a pathophysiological basis for the clinically observed differences between the two calcineurin inhibitors."
Journal • Cardiovascular • Hypertension • CALB1 • EDN1 • EGF
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A H Jan Danser; Ewout J Hoorn; Hester van Willigenburg; Jennifer L Cross; Jeroen H F de Baaij; John J Viel; Kuang-Yu Wei; Linda M Rehaume; Martijn H van Heugten; Pedro Henrique Imenez Silva; Richard van Veghel; Wouter H van Megen
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