Management of systemic lupus erythematosus with kidney involvement: systematic literature review to inform the 2025 update of EULAR recommendations. (PubMed, EULAR Rheumatol Open) - Jun 30, 2026 - "A combination of 2 immunosuppressive agents, such as belimumab with mycophenolate mofetil (MMF)/cyclophosphamide, voclosporin with MMF, or obinutuzumab with MMF, is associated with higher response rates, based on high-quality randomised controlled trials (RCTs). Patients who respond within the first year of treatment tend to have better long-term outcomes. Kidney biopsy is essential for diagnosis, but the role of repeat biopsy awaits confirmation from higher-quality studies."
Journal • Review • Glomerulonephritis • Immunology • Inflammatory Arthritis • Lupus • Lupus Nephritis • Nephrology • Renal Disease • Rheumatology • Systemic Lupus Erythematosus
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Antonis Fanouriakis; Carlo Alberto Scirè; Dimitrios T Boumpas; George Bertsias; Myrto Kostopoulou
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