Rapid Reduction in Proteinuria With the Initiation of Voclosporin in Lupus Nephritis: A Single-Center Experience. (PubMed, Cureus) - Apr 22, 2026 - "Results Twenty‑five patients with biopsy‑proven LN were treated with voclosporin; all received concurrent hydroxychloroquine and tolerated voclosporin without discontinuation. Most patients were treated with mycophenolate or mycophenolic acid (92%) and corticosteroids (96%; median prednisone‑equivalent dose 15 mg/day). To our knowledge, this represents the largest case series to date describing early real‑world outcomes with voclosporin in LN. Given that persistent proteinuria may indicate ongoing renal inflammation and/or chronic damage, these findings support consideration of voclosporin as a first‑line therapeutic option for active LN."
Journal • Glomerulonephritis • Immunology • Inflammation • Inflammatory Arthritis • Lupus • Lupus Nephritis • Nephrology • Renal Disease • Systemic Lupus Erythematosus
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Boyoung Ahn; Duvuru Geetha; Homa Timlin; Ihab Kamel; Johnson Ong; Mohamed G Atta; Timothy Kaniecki
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