Benlysta (belimumab) - GSK
Lupkynis (voclosporin) - Aurinia Pharma
Gazyva (obinutuzumab) - Roche, Biogen
cyclophosphamide - Generic mfg.
mycophenolate mofetil - Generic mfg.
ianalumab (VAY736) - Novartis
Saphnelo (anifrolumab-fnia) - AstraZeneca
Recent advances in immunosuppressive therapy for lupus nephritis. (PubMed, Immunol Med) - Jan 7, 2026 - "Triple therapy, which combines mycophenolate mofetil (MMF) with belimumab (BEL) or calcineurin inhibitors (CNIs, including voclosporin), or intravenous cyclophosphamide with BEL, has been recommended, particularly for active nephritis with poor prognostic factors...Furthermore, the latest treatment recommendations from the European League Against Rheumatism had added the combination therapy of MMF plus obinutuzumab as an initial treatment option. In this review, we discuss the latest guidelines and recommendations for LN." 
Journal • Review • Glomerulonephritis • Immunology • Inflammatory Arthritis • Lupus • Lupus Nephritis • Nephrology • Renal Disease • Rheumatology • Systemic Lupus Erythematosus
http://www.ncbi.nlm.nih.gov/pubmed/41498488
 
Michihito Kono; Shuhei Takeyama
 
Jan 7, 2026
 
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