Structure-based design and synthesis of KX-01 analogs as potent antitumor agents targeting the tubulin colchicine binding site.

tirbanibulin oral (KX-01 oral) - Athenex

colchicine - Generic mfg.

http://www.ncbi.nlm.nih.gov/pubmed/42001543

Chenke Gao; Chufeng Zhang; Fang Wang; Hongxiu Chen; Jianhong Yang; Li Liu; Maoru Sun; Minghai Tang; Qingqing Li; Shuai Zhang; Xiuying Hu; Xue Cui; Yilin Wang; Yong Li; Zhuang Yang

Apr 21, 2026