Case Report: Panic attacks after tirzepatide injection in two female patients with recurrent depressive disorder. (PubMed, Front Drug Saf Regul) - Oct 27, 2026 - "Tirzepatide was introduced several years ago for the management of obesity...No clear medical aetiology was identified. Changes in pharmacokinetics by delayed gastric emptying, GABAergic deficits, an activation of the nucleus of the solitary tract (NTS) or activation of the hypothalamus-pituitary-adrenal axis are considered as potential mechanisms for panic attacks."
Journal • CNS Disorders • Depression • Genetic Disorders • Mental Retardation • Mood Disorders • Obesity • Psychiatry • Suicidal Ideation
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Hubertus Himmerich; Markus Backmund; Ulrich Palm
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