Erbitux (cetuximab) - Eli Lilly
A YopJ-family effector from Ralstonia solanacearum is associated with auxin-responsive transcriptional reprogramming and bacterial wilt suppression. (PubMed, Plant Physiol) - Sep 29, 2026 - "Mutations in conserved residues H158 and C225 strongly impaired RipBR-associated hypersensitive response induction and disease suppression, indicating their importance for RipBR function...Exogenous 1-naphthaleneacetic acid (NAA) treatment alleviated bacterial wilt symptoms but did not significantly reduce bacterial colonization, indicating that auxin signaling activation alone is insufficient to establish enhanced resistance. Together, these findings identify RipBR as a YopJ-family effector associated with bacterial wilt suppression in potato and reveal an association between effector recognition and auxin-responsive transcriptional reprogramming during plant immunity." 
Journal
http://www.ncbi.nlm.nih.gov/pubmed/42804676
 
Bingsen Wang; Botao Song; Hongxu Zhu; Huilan Chen; Jiahui Wu; Jingxin Liu; Juan Du; Liu Yu; Mengshu Huang; Qian Li; Xiaodan Tan; Yuhan Li
 
Sep 29, 2026
 
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