A Case of Nephrotic Syndrome Developing Early After Initiation of Fruquintinib Therapy (PubMed, Yakugaku Zasshi) - Oct 1, 2026 - "loxoprofen and magnesium oxide were discontinued and furosemide was initiated...The Naranjo score were 7 for fruquintinib, 6 for loxoprofen and bevacizumab, and 5 for trifluridine/tipiracil hydrochloride, suggesting probable adverse drug reaction...Although renal biopsy was not performed, thrombocytopenia and elevated lactate dehydrogenase suggested thrombotic microangiopathy. Earlier monitoring could have enabled faster detection and prevention of severe symptoms."
Journal • Cardiovascular • Colorectal Cancer • Dermatology • Fatigue • Glomerulonephritis • Hematological Disorders • Hypertension • Nephrology • Oncology • Pulmonary Disease • Renal Disease • Solid Tumor • Thrombocytopenia
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Akihiro Tamura; Atsushi Ohkawara; Eri Ogawa; Mika Urushima; Wataru Sato; Yuka Aimono; Yusuke Harada
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