Triple incretin agonist retatrutide reduces alcohol reward, consumption, and relapse-like drinking in rodents (Neuroscience 2026) - Sep 27, 2026 - Abstract #PSTR375.10 / KK10; Pres time: Nov 18, 2026; 01:00 PM - 05:00 PM; Location: WCC Halls A-C; "Furthermore, acute retatrutide administration significantly reduced voluntary alcohol consumption and prevented relapse-like drinking following alcohol deprivation in both male and female rats, accompanied by reduced food intake and body weight, suggesting additional effects on ingestive behavior. Together, these findings identify retatrutide as a promising candidate for the pharmacological treatment of AUD and support further evaluation in clinical settings."
Preclinical • Addiction (Opioid and Alcohol) • CNS Disorders
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A. LOFTÉN1,2; C. EDVARDSSON3; S. ALFREJI4; C. ARANÄS4; S. WITLEY4; T. ARCEBISPO EMOUS4; E. JERLHAG4
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