Zonisamide attenuates morphine tolerance in association with reduced spinal TLR4/p38 MAPK signaling.

morphine sulphate - Generic mfg.

zonisamide - Generic mfg.

resatorvid (TAK-242) - Takeda, Akaza Bioscience

http://www.ncbi.nlm.nih.gov/pubmed/42718972

Dong-Tai Chen; Hong Guo; Hong-Xia Cheng; Juan-Juan Feng; Li-Ba Gei; Lu-Lu Li; Ri-Qi E; Rui Zhang; Wei-An Zeng; Xin Zhao; Yan Yan; Ying-Hua Liu

Sep 11, 2026