Alecensa (alectinib) - Roche
Xalkori (crizotinib) - Pfizer
Ensacove (ensartinib) - Betta Pharma
Lorbrena (lorlatinib) - Pfizer
Qi Xinke (iruplinalkib) - Qilu Pharma
Alunbrig (brigatinib) - Takeda
Cost-Effectiveness Analysis of the Five First-line Treatment Regimens for ALK-positive NSCLC in China: An Economic Evaluation Based on Network Meta-Analysis. (PubMed, Value Health) - Sep 22, 2026 - "For patients with advanced ALK-positive NSCLC in China, lorlatinib, alectinib, brigatinib, and iruplinalkib are cost-effective compared to crizotinib, with the exception of ensartinib. Among these, iruplinalkib is the most cost-effective TKI for first-line treatment, followed by lorlatinib." 
HEOR • Journal • Retrospective data • Lung Cancer • Non Small Cell Lung Cancer • Oncology • Solid Tumor • ALK
http://www.ncbi.nlm.nih.gov/pubmed/42767340
 
Bikun Cai; Guihao Zeng; Hui Zhang; Jing Ou; Shuangshuang Hu; Yuhang Liu
 
Sep 22, 2026
 
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