Transcriptomic changes and mitochondrial toxicity in response to acute and repeat dose treatment with brequinar in human liver and kidney in vitro models.

brequinar (DUP 785) - BMS, Clear Creek Bio

http://www.ncbi.nlm.nih.gov/pubmed/39900124

Anja Wilmes; Barira Islam; Barry Hardy; Bas Ter Braak; Bob van de Water; Iain Gardner; Ilinca Suciu; Liesanne Loonstra-Wolters; Marcel Leist; Oliver Hatley; Paul Jennings; Richard Currie; Steven J Kunnen; Tamara Meijer

Feb 4, 2025