Picropodophyllin induces ferroptosis via blockage of AKT/NRF2/SLC7A11 and AKT/NRF2/SLC40A1 axes in hepatocellular carcinoma as a natural IGF1R inhibitor.

picropodophyllin (AXL1717) - Axelar

deferoxamine - Generic mfg.

http://www.ncbi.nlm.nih.gov/pubmed/40412057

Dan Guo; Fengchi Zhu; Jiahui Zheng; Mengting Liu; Nana Chen; Sha Liu; Xiangping An; Yan Yao; Yixin Liu; Zhuo Cai

May 25, 2025