Respiratory and antinociceptive effects of NOP-MOP agonist cebranopadol versus full opioid receptor agonist oxycodone: a comparison in healthy volunteers. (PubMed, Anesthesiology) - Dec 11, 2025 - "The primary endpoint showed separation between the respiratory effects of cebranopadol and oxycodone, with 25% less respiratory depression at equianalgesia, as observed in the pharmacokinetic/pharmacodynamic analysis."
Clinical • Journal • CNS Disorders • Depression • Pain • Psychiatry
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Albert Dahan; Elise Sarton; Erik Olofsen; Geert Jan Groeneveld; James C Hackworth; Joseph C Grieco; Laurence Moss; Marc L Lesnick; Marieke Niesters; Monique van Velzen; Rutger van der Schrier; Simone Jansen
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