Mechanism and therapeutic significance of ARV-110 combined with a PDGFR inhibitor for the induction of apoptosis in castration-resistant prostate cancer cells through the ROS/JNK pathway.

bavdegalutamide (ARV-110) - Arvinas

Iclusig (ponatinib) - Takeda

http://www.ncbi.nlm.nih.gov/pubmed/41963300

Chiyuan Piao; Guangxu Liu; Haoyuan Zheng; Jianbin Bi; Qingzhuo Dong; Shanshan Sun; Yang Fu; YuTao Wang

Apr 11, 2026