Case Report: Periungual Xeligekimab injection for refractory Acrodermatitis continua of Hallopeau. (PubMed, Front Immunol) - Mar 20, 2026 - "Prior therapies, including topical corticosteroids, phototherapy, and systemic tofacitinib, had proven ineffective. This escalation resulted in marked clinical resolution: complete clearance of pustules and inflammation, healthy nail regrowth, and resolution of digital swelling and pain. Concurrently, the Dermatology Life Quality Index and pain scores dramatically improved, and follow-up MRI showed substantial resolution of the underlying bone marrow edema, confirming the treatment's efficacy on both cutaneous and deep osseous inflammation."
Journal • Dermatitis • Dermatology • Immunology • Inflammation • Pain • IL17A
|
|
Aijie Yuan; Chen Li; Jingchen Yang; Peng Cao; Tao Guo; Yuning Zhang
|