ligelizumab (QGE 031) - Novartis
Xolair (omalizumab) - Roche, Novartis
UB-221 - United BioPharma
quilizumab (MEMP1972A) - Roche
Anti-IgE for the Treatment of Chronic Urticaria. (PubMed, Immunotargets Ther) - Feb 26, 2021 - "Phase 2 b results of ligelizumab have not only demonstrated efficacy and safety but also superiority to omalizumab. Whereas further development of quilizumab was discontinued, other approaches, eg UB-221 or DARPins are under investigation. Anti-IgE treatment with omalizumab represents a landmark in the treatment of chronic urticaria, with and without angioedema, and there is light on the horizon suggesting success may come with various next-generation anti-IgE approaches." 
Clinical • Journal • Review • Cardiovascular • Chronic Spontaneous Urticaria • Dermatology • Urticaria
http://www.ncbi.nlm.nih.gov/pubmed/33628747
 
Feb 26, 2021
 
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