EFFICACY AND SAFETY OF ADVANCED THERAPIES AS INDUCTION THERAPY FOR ULCERATIVE COLITIS: AN UPDATED SYSTEMATIC REVIEW AND NETWORK META-ANALYSIS. (PubMed, Clin Gastroenterol Hepatol) - Oct 7, 2026 - "Upadacitinib has high efficacy for induction of clinical remission and endoscopic improvement in AT-naïve and AT-experienced patients. Novel therapies, like obefazimod and guselkumab subcutaneous, may represent highly effective alternatives. Anti-p19 inhibitors offer a favorable safety profile."
Journal • Retrospective data • Review • Gastroenterology • Gastrointestinal Disorder • Immunology • Infectious Disease • Inflammatory Bowel Disease • Ulcerative Colitis
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Bruce E Sands; Juan S Lasa; Laurent Peyrin-Biroulet; Mathurin Fumery; Pablo A Olivera; Siddharth Singh; Silvio Danese; Vipul Jairath
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