PERIPHERAL BLOOD FLOW CYTOMETRY IDENTIFIES EARLY CHANGES IN CIRCULATING ERYTHROID PRECURSORS ANTICIPATING LOSS OF RESPONSE AND LEUKEMIC EVOLUTION IN LUSPATERCEPT-TREATED MDS (SIE 2026) - Oct 6, 2026 - Abstract #SP120; "Peripheral blood FC may detect early changes in the erythroid compartment during Luspatercept therapy, before both loss of hematologic response and leukemic evolution. Although erythroid maturation is not routinely assessed in peripheral blood, repeated evaluation of circulating erythroid precursors may provide additional in- formation on disease course and help anticipate clinical pro- gression in patients with MDS."
Acute Myelogenous Leukemia • Hematological Malignancies • Leukemia • Myelodysplastic Syndrome • PTPRC • SF3B1
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M. Greco1; A. M. Mereu2; G. Paci1; M. Moi2; M. Schintu2; B. Coci2; A. Fois2; M. L. Cogoni2; A. Frau1; G. A. Porcu2; G. Serra1; F. Pilo1; M. Pettinau1; C. Romani1; G. Caocci1,2
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