izalontamab brengitecan (BL-B01D1) - Sichuan Biokin Pharmaceutical, BMS, Systimmune
Achievement of a milestone in the global Phase III registration trial IZABRIGHT-Lung02 has triggered a USD 250 million near-term milestone payment to SystImmune, Inc. under its collaboration with Bristol Myers Squibb (AllSci Corp) - Sep 23, 2026 - "The payment represents the second USD 250 million tranche under the agreement, alongside an USD 800 million upfront payment received after the deal was signed in December 2023. IZABRIGHT-Lung02 is a BMS-led global registrational Phase III study evaluating izalontamab brengitecan (iza-bren), an EGFRxHER3 bispecific antibody-drug conjugate (ADC), in previously untreated patients with locally advanced or metastatic EGFR-mutant non-small cell lung cancer (NSCLC)....Biokin did not disclose the specific milestone event that triggered the payment, and the announcement included no clinical efficacy or safety data." 
Financing • Non Small Cell Lung Cancer
https://allsci.com/news/systimmune-phase-iii-lung-cancer-trial-hits-usd/
 
Sep 23, 2026
 
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