Orofacial granulomatosis associated with Crohn's disease: clinical phenotype and response to biologics and Janus kinase inhibitor therapy in a large multi-center cohort. (PubMed, J Crohns Colitis) - Sep 23, 2026 - "OFG is associated with a distinct CD phenotype characterized by frequent UGI and perianal involvement. Advanced therapies, including anti-TNF, anti-IL23, and JAKi therapies, are effective, with evidence supporting dose optimization."
Journal • Retrospective data • Crohn's disease • Gastroenterology • Gastrointestinal Disorder • Immunology • Inflammatory Bowel Disease
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Angelica Molinillo Marin; Cameron Herbert; Christopher A Lamb; Daniel Parkinson; Esther Hullah; Gregory Young; Jeremy Sanderson; Joel Mawdsley; Laetitia Pele; Lauren Beck; Miles Parkes; Priyanka Patel; Richard Ally Speight; Robert D Lees
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