Case Report: Neuroretinitis following combination checkpoint inhibition therapy with nivolumab and ipilimumab for stage IIIC melanoma. (PubMed, Front Oncol) - Sep 19, 2026 - "The patient was treated with intravenous methylprednisolone (IVMP) pulse and intravenous immunoglobulin (IVIG) at initial hospitalization, followed by a slow oral prednisone taper along with monthly IVIG outpatient. Prompt recognition, exclusion of infectious mimics, and multidisciplinary management can yield meaningful visual recovery. Comprehensive neuro-ophthalmic assessment for ICI-associated neuro-ophthalmic complications including evaluation of color vision and pupillary function, documentation of fundus appearance, and additional ancillary testing with visual field and OCT analysis is essential."
Checkpoint inhibition • Journal • Cutaneous Melanoma • Genetic Disorders • Hematological Disorders • Macular Edema • Melanoma • Ocular Infections • Ocular Inflammation • Oncology • Ophthalmology • Retinal Disorders • Solid Tumor
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Aaron B Roller; Jared Moon; Moe H Aung; Nuha S Arefin
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