A Case of Immune Checkpoint Inhibitor-Induced Overlap Syndrome with Clinical Pearls for the Nephrologist (KIDNEY WEEK 2026) - Oct 2, 2026 - Abstract #PUB201; "Case Description A 57 year old female with uterine serous adenocarcinoma and recent carboplatin/paclitaxel/dostarlimab treatment presented with shortness of breath, chest pain, and weakness...She received treatment with high dose steroids and Abatacept followed by 1 session of plasma exchange (PLEX)...Plasmapheresis can both remove pathological antibodies from blood and promote rapid clearance of circulating drugs making early Nephrology engagement imperative. In our case, we could not confirm presence of myasthenia gravis, but there is speculation that autoimmune encephalitis may represent an unrecognized variant of ICI-induced overlap syndrome."
Checkpoint inhibition • Clinical • Cardiovascular • CNS Disorders • Immunology • Infectious Disease • Myasthenia Gravis • Myositis • Nephrology • Oncology • Respiratory Diseases • Uterine Cancer
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Emily Rose Hargous; Curtis Anthony Hendrix; Milos N. Budisavljevic
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