Opdivo (nivolumab) - Ono Pharmaceutical, BMS
Adcetris (brentuximab vedotin) - Takeda, Pfizer
Controversies in the Management of Early-Stage Hodgkin Lymphoma: The Role of Radiation Therapy. (PubMed, J Natl Compr Canc Netw) - Sep 18, 2026 - "Meanwhile, novel agents such as nivolumab and brentuximab vedotin have significantly advanced the treatment of advanced-stage disease and are now demonstrating promising activity in early-stage Hodgkin lymphoma. Techniques such as proton therapy, intensity-modulated RT, and image-guided RT dramatically reduce radiation exposure to healthy tissues compared with historical approaches, thereby improving the therapeutic ratio. Despite the high cure rates achieved today, clinical trials continue to explore novel and personalized approaches to achieve long-term remission without compromising quality of life." 
Journal • Review • Hematological Malignancies • Hodgkin Lymphoma • Lymphoma • Oncology
http://www.ncbi.nlm.nih.gov/pubmed/42753815
 
Christopher R Kelsey; Yorleny Vicioso Mora
 
Sep 18, 2026
 
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