LEA29Y expression executes a heterogenous protective effect on cardiac transplants in a porcine allograft model (TTS 2026) - Sep 17, 2026 - Pres time: Sep 23, 2026; 08:51 AM - 09:00 AM; Location: Cockle Bay 2; 402; "Pre-existing immune activation may serve as a strong predictive marker for post-transplant rejection responses. Retrospective single nuclei RNAseq analysis will give detailed insight into the underlying mechanisms of immune response pre-disposition and help to determine synergistic angles to support local T-cell co-stimulation blockade."
Preclinical • Immunology • Transplant Rejection • Transplantation • ADAM17 • CD68 • HLA-DRB1 • IFNG • IL10 • IL18 • IL1A • IL1B • IL6 • MYH7 • PTPRC • RYR2 • TNFA
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Sebastian Michel1; Samjhana Shrestha2,3; Nadja Hornaschewitz2,3; Constanca Figueiredo4; Sabine Hammer5; Eckhard Wolf2; Bruno Reichart1; Daniel Reichart1; Nikolai Klymiuk2,3; Andrea Bähr2,3
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