Metastasis-directed local therapy and strategic de-escalation of systemic therapy for oligometastatic esophageal squamous cell carcinoma. (PubMed, Jpn J Clin Oncol) - Sep 17, 2026 - "This course is analogous to postoperative nivolumab after chemoradiotherapy...CtDNA may eventually guide the timing of treatment interruption and rechallenge. We discuss the rationale, current limitations, and prospective validation needs for this strategy in the multidisciplinary management of ESCC."
IO biomarker • Journal • Esophageal Cancer • Esophageal Squamous Cell Carcinoma • Gastric Adenocarcinoma • Gastric Cancer • Gastroesophageal Junction Adenocarcinoma • Oncology • Solid Tumor • Squamous Cell Carcinoma
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Hiroya Takeuchi; Katsuyuki Sakanaka; Kazuaki Matsui; Ken Kato; Mitsuhiro Furuta; Mitsuro Kanda; Motoo Nomura; Satoru Matsuda; Takahiro Tsushima; Takako Yoshii; Takashi Ogata; Yasuhiro Tsubosa; Yoichi Hamai
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