Machine learning integrated explainable artificial intelligence in predicting toxicities of enfortumab vedotin in urothelial carcinoma: an exploratory study. (PubMed, Expert Rev Anticancer Ther) - Sep 13, 2026 - "SHAP showed atezolizumab/nivolumab linked to lower cutaneous risk, and female sex to higher risk. These preliminary, hypothesis-generating findings suggest ML may predict EV-related toxicities, but single train-test split, small event counts, and lack of external validation preclude clinical use. Prospective validation is essential."
Journal • Diabetes • Diabetic Neuropathy • Metabolic Disorders • Oncology • Pain • Solid Tumor • Urothelial Cancer
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Andrea Malgeri; Aristotelis Bamias; Brigida Anna Maiorano; Daniele Santini; Fabio Calabrò; Gian Paolo Spinelli; Gowri Sivaramakrishnan; Jawaher Ansari; Jindrich Kopecky; Kannan Sridharan; Linda Cerbone; Luca Zacco; Matteo Santoni; Mattia Alberto Di Civita; Se Hoon Park; Takafumi Yanagisawa; Takahiro Kimura; Tarek Taha; Tomas Buchler; Wataru Fukuokaya
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