Predicting Targeted and Immunotherapeutic Response Outcomes in Melanoma With Single-Cell Raman Spectroscopy and Artificial Intelligence. (PubMed, JCO Precis Oncol) - Sep 10, 2026 - "Single-cell Raman spectroscopy combined with ML offers a scalable, prognostic platform to predict therapeutic resistance likelihood, with further potential to advance clinical, multiomic biomarker efforts for melanoma. Our approach may improve first- and second-line therapy selection assessments for precision medicine by providing rapid, nondestructive prediction of therapeutic response based on cellular spectral profiles."
IO biomarker • Journal • Melanoma • Oncology • Solid Tumor
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Amanda Gonçalves; Amanda Kirane; Ariel Stiber; Baba Ogunlade; Daniel Delitto; Fareeha Safir; Grayson E Rodriguez; Hsiu-Ju Hsu; James Agolia; Jay Chadokiya; Jeffrey Gu; Jennifer A Dionne; K Christopher Garcia; Kai Chang; Mamatha Serasanambati; Nhat Vu; Ojasvi Verma; Prabhjeet Singh; Saurabh Sharma
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