Astragalus membranaceus-derived exosomes alleviate traumatic brain injury by inhibiting SERPINE1/HIF-1α/NLRP3-mediated pyroptosis. (PubMed, Behav Brain Res) - Sep 10, 2026 - "These findings demonstrate that AM-derived exosomes represent a promising therapeutic approach for TBI by suppressing pyroptosis and facilitating functional recovery through inhibition of the SERPINE1/HIF-1α/NLRP3 axis."
Journal • CNS Disorders • Vascular Neurology • HIF1A • IL18 • IL1B • NLRP3 • SERPINE1
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Chao Li; Jinlong Lyu; Peng Sun; Zhengluan Liao
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