Yervoy (ipilimumab) - BMS
Opdivo (nivolumab) - Ono Pharmaceutical, BMS
Fulminant blood sugar increase - a rare but life-threatening course (PubMed, Praxis (Bern 1994)) - Sep 9, 2026 - "A 71-year-old patient with known metastatic melanoma undergoing treatment with the immune checkpoint inhibitors Ipilimumab/Nivolumab presented with a rapid deterioration in general condition over the past 24 hours. We hereby diagnosed fulminant ICI- associated type 1 diabetes mellitus. Symptoms improved under insulin therapy." 
Journal • Diabetes • Endocrine Disorders • Melanoma • Metabolic Disorders • Oncology • Solid Tumor • Type 1 Diabetes Mellitus
http://www.ncbi.nlm.nih.gov/pubmed/42708199
 
Moritz Sigg; Stefan Bilz; Stefan Diem
 
Sep 9, 2026
 
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