Ketogenic diet-induced changes in hepatic drug metabolism with potential implications for ozanimod pharmacokinetics in mice. (PubMed, PLoS One) - Sep 9, 2026 - "In conclusion, our findings demonstrate that KD altered the expression and activity of hepatic CYP enzymes and revealed a non-significant trend toward increased ozanimod exposure. These observations highlight the potential importance of considering dietary interventions as a factor contributing to variability in drug response."
Journal • PK/PD data • Preclinical • CNS Disorders • Multiple Sclerosis • CYP2C19
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Eva Anzenbacherova; Iveta Zapletalova; Klara Kostovcikova; Lenka Jourova; Michal Kraus; Miloslav Kverka; Pavel Anzenbacher; Stefan Satka; Veronika Frybortova
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