M5542, a bifunctional fusion protein targeting CD80, CD86, and OX40L that modulates excessive T-cell activity: a preclinical proof-of-concept study.

M5542 - EMD Serono

Orencia (abatacept) - BMS

http://www.ncbi.nlm.nih.gov/pubmed/42718826

Aditee Deshpande; Alec W Gross; Allison Christiaansen; Chia Chi Sun; Gang Chen; Hong Zhang; Katherine Roe; Ling Zhang; Maria Soloviev; Michelle Downing; Mira Toister-Achituv; Namita Kumar; Ohad Tarcic

Sep 11, 2026