Artemether induces JNK1/FOXO1/GPX4-mediated ferroptosis to suppress colorectal cancer. (PubMed, Tissue Cell) - Oct 14, 2026 - "Artemether inhibits CRC and alleviates tumor-associated inflammation by inducing JNK1/FOXO1/GPX4-mediated ferroptosis, validated pharmacologically and genetically, highlighting its potential as an immunomodulatory anticancer agent."
Journal • Colorectal Cancer • Oncology • Solid Tumor • GPX4 • IL18 • IL1B • IL6 • MAPK8 • TNFA
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Boyun Zeng; Chunmao Xie; Hu Lu; Lv Ge; Qianqian Liu; Qiong Lin; Shenglan Yu; Zhiyi Xiao; Zhuo Gao
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