Yervoy (ipilimumab) - BMS
oxaliplatin - Generic mfg.
5-fluorouracil - Generic mfg.
Opdivo (nivolumab) - Ono Pharmaceutical, BMS
irinotecan - Generic mfg.
A Phase II Study of Nivolumab and Ipilimumab with Radiation Therapy in Patients with Metastatic, Microsatellite Stable Colorectal Cancer. (PubMed, Clin Cancer Res) - Oct 2, 2026 - "The combination of immune-modulating, non-ablative doses of radiation therapy with ipilimumab and nivolumab has selective clinical activity in refractory MSS CRC, with responses concentrated primarily in patients without active liver metastases." 
Journal • P2 data • Colorectal Cancer • Microsatellite Instability • Oncology • Solid Tumor • MSI
http://www.ncbi.nlm.nih.gov/pubmed/42820689
 
Aparna R Parikh; Arnav Mehta; Benjamin L Schlechter; Beow Y Yeap; Bruce J Giantonio; David P Ryan; David Ting; Elizabeth Kantrowitz; Hannah J Roberts; Jeffrey A Meyerhardt; Jeffrey W Clark; Jennifer Y Wo; Jill N Allen; Julie L Koenig; Katharine Zecca; Kimberly Perez; Lawrence S Blaszkowsky; Leontios Pappas; Lorraine C Drapek; Ryan Corcoran; Samuel J Klempner; Sydney D Ludes; Theodore S Hong
 
Oct 2, 2026
 
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