Strategic selection of MDM2 inhibitors enhances the efficacy of FAK inhibition in mesothelioma based on TP53 genotype.

RITA - Aprea

Fakzynja (defactinib) - Verastem

http://www.ncbi.nlm.nih.gov/pubmed/41729969

Hideaki Shimada; Kenzo Hiroshima; Masatoshi Tagawa; Naoto Yamaguchi; Takao Morinaga; Xuerao Ning; Yuji Tada

Feb 23, 2026