Taraxasterol alleviates osteoporosis by targeting PI3K/AKT/PPARγ signaling axis to suppress necroptosis and reverse osteogenic-adipogenic differentiation imbalance in BMSCs.

LY294002 - Eli Lilly

SM-164 - Ascenta

http://www.ncbi.nlm.nih.gov/pubmed/41317432

Chenying Zeng; Jiajie Lin; Linjian Chen; Qibo Li; Qingqiang Tu; Weihao Zhang; Wenhui Yu; Yanfeng Wu; Zhongyu Xie; Ziji Zhang; Zipeng Xiao

Nov 30, 2025