Combination synergy of spliceosome modulator ADC with a K-Ras inhibitor in K-Ras –mutated pancreatic cancers.

Trodelvy (sacituzumab govitecan-hziy) - Gilead

Jiataile (sacituzumab tirumotecan) - Merck (MSD)

Krazati (adagrasib) - BMS

Datroway (datopotamab deruxtecan-dlnk) - Daiichi Sankyo, AstraZeneca

AKTX-101 - Akari Therap

https://www.asco.org/abstracts-presentations/265169/

Satyajit Mitra; Mastewal Abuhay; Howard Stern

Apr 21, 2026