Rezzayo (rezafungin for injection) - Mundipharma, Melinta Therap, Merck (MSD)
Brexafemme (ibrexafungerp) - GSK
fosmanogepix (APX001) - Basilea
Multidrug Resistance and Host Adaptation in Candida Auris: From Molecular Mechanisms to Emerging Therapeutic Frontiers. (PubMed, Mycopathologia) - Oct 4, 2026 - "To overcome these formidable MDR bottlenecks, therapeutic paradigms are rapidly evolving. The integration of next-generation antifungals such as the long-acting echinocandin rezafungin, fosmanogepix, and ibrexafungerp, synergistic combination therapies, quorum-sensing inhibitors such as farnesol, and experimental nanocarrier delivery systems could represent promising frontiers to effectively dismantle the complex defense networks of C. auris." 
Journal • Review • CDC37 • HSP90AA1 • IL17A • S100A8
http://www.ncbi.nlm.nih.gov/pubmed/42828654
 
FengLin Shao; Jingjing Su; Tingru Wu
 
Oct 4, 2026
 
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