Best Anti-Fungal Prophylaxis and Treatment Pre-/Post-HSCT (ICBMT 2026) - Oct 8, 2026 - Abstract #ES02-2; Pres time: Sep 18, 2026; 10:40 AM - 11:10 AM; Location: Room D(2F); "In acute myeloid leukemia remission-induction therapy, mold-active prophylaxis remains standard, with posaconazole as the preferred agent, whereas itraconazole has been downgraded...In acute lymphoblastic leukemia, mold-active triazoles are generally discouraged during vincristine-containing therapy because of clinically important drug–drug interactions and the risk of neurotoxicity; prophylactic strategies should therefore account for both the individual mold risk and potential vincristine interactions...For proven or probable invasive aspergillosis, voriconazole and isavuconazole are first-line; liposomal amphotericin B is the principal alternative, and echinocandin-containing combinations are reserved for selected severe cases. For invasive candidiasis and candidemia, an echinocandin is first-line, with step-down to fluconazole guided by species and susceptibility...Emerging issues and stewardship Cross-cutting themes include therapeutic drug monitoring for..."
Acute Lymphocytic Leukemia • Acute Myelogenous Leukemia • Bone Marrow Transplantation • Candidiasis • Febrile Neutropenia • Graft versus Host Disease • Hematological Malignancies • Immunology • Infectious Disease • Leukemia • Lymphoma • Multiple Myeloma • Myelodysplastic Syndrome • Neutropenia • Respiratory Diseases
|