Gilteritinib-Associated Hypertriglyceridemia During Acute Myeloid Leukemia Triplet Therapy in a 52-Year-Old Man: A Case Report. (PubMed, Cureus) - Aug 1, 2026 - "We describe a case of profound hypertriglyceridemia that developed during treatment with a combination of azacitidine, venetoclax, and gilteritinib...Gilteritinib, venetoclax, and isavuconazole were discontinued, and lipid-lowering therapy with rosuvastatin and fenofibrate was commenced...This report draws attention to a potentially serious and insufficiently recognized metabolic complication associated with FLT3 inhibitor-based combination therapy. It also underscores the importance of routine lipid surveillance, particularly in patients receiving concomitant azole antifungal agents."
Journal • Acute Myelogenous Leukemia • Dyslipidemia • Hematological Malignancies • Hypertriglyceridemia • Infectious Disease • Leukemia • Metabolic Disorders • Oncology • Pancreatitis • Pneumonia • Respiratory Diseases • DNMT3A • FLT3 • NPM1
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Bhargav Vuppumalla; Chaitanya Kumar Javvaji; Karna Jagatheeswaran; Prabhath Surya Katta; Steve Thomas
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