Exploratory model-based optimizing isavuconazole dosing regimens for Aspergillus spp. in adult patients according to serum albumin levels: a pharmacokinetic/pharmacodynamic analysis using Monte Carlo simulation. (PubMed, Front Cell Infect Microbiol) - Jul 4, 2026 - "However, the majority of simulating dosing regimens failed to achieve the desired CFR values against A. niger. These PK/PD simulations support isavuconazole dose optimization for hypoalbuminemic adults with aspergillosis and require prospective clinical validation."
Journal • PK/PD data • Pulmonary Disease • Respiratory Diseases
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Hai-Rong Lyu; Ming-Feng Zhao; Xia Xiao; Xiao-Chen Wei
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