Manogepix demonstrates potent in vitro activity against Aspergillus, Coccidioides, Scopulariopsis/Microascus, Rasamsonia, and Purpureocillium species, including strains with in vitro resistance to other antifungals.

Cresemba (isavuconazonium sulfate) - Astellas, Basilea

fluconazole oral - Generic mfg.

Noxafil (posaconazole) - Merck (MSD)

fosmanogepix (APX001) - Basilea

itraconazole - Generic mfg.

http://www.ncbi.nlm.nih.gov/pubmed/42240332

Carmita Sanders; Connie Cañete-Gibas; Hoja P Patterson; Nathan P Wiederhold

Jun 5, 2026