Establishment of epidemiological cutoff values against Fonsecaea monophora, an agent of chromoblastomycosis and cerebral phaeohyphomycosis. (PubMed, J Clin Microbiol) - Jun 26, 2026 - "AFST was performed by CLSI M38 standard broth microdilution method for itraconazole, voriconazole, posaconazole, isavuconazole, ketoconazole, terbinafine, flucytosine, and amphotericin B. The ECVs were established using the iterative statistical method with ECOFFinder (v2.1) following CLSI M57 guidelines. The calculated ECVs for commonly used antifungals were 2 μg/mL for itraconazole, 0.25 μg/mL for voriconazole, 1 μg/mL for posaconazole, and 0.5 μg/mL for terbinafine. ECVs can assist in selecting potential treatments for F. monophora and tracking antifungal resistance trends."
Journal • CNS Disorders • Dermatology • Infectious Disease
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Alexandro Bonifaz; Amir Seyedmousavi; Anuradha Chowdhary; Arghadip Samaddar; Arunaloke Chakrabarti; Bram Spruijtenburg; Bruna Jacomel; Bruno P R Lustosa; Conceicão de Maria Pedrozo E Silva de Azevedo; Dallas J Smith; Daniel Wagner C L Santos; Diptanu Paul; Eelco F J Meijer; Elias Nunes Monteiro Neto; Ferry Hagen; Flávio Queiroz-Telles; Gloria M González; Guillermo Garcia-Effron; Harsimran Kaur; José Guillermo Pereira Brunellie; Nathan P Wiederhold; Nimmy Paul; Philippe J Dufresne; Regielly C R Cognialli; Rodrigo Almeida-Paes; Rogelio de J Treviño-Rangel; Ruoyu Li; Sarah E Kidd; Sha Lu; Shawn R Lockhart; Shivaprakash M Rudramurthy; Sirlei Garcia Marques; Theun de Groot; Thiago Henrique Walter; Tijmen van Beurden; Vania Aparecida Vicente; Vinaykumar Hallur; Yalong Li; Yinggai Song
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